To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Figures Fig. 1 Schematic illustrating the time course and experimental design of Experiments 1-3. In Experiments 1 (males) and 2 (females) a CTA design was employed in which animals were habituated to 30 min water access following nicotine or saline administration. Following habituation, animals were conditioned to the effects of their assigned drug US through pairing with 0.1% saccharin. Each conditioning day was followed by a non-conditioning day on which animals were given water to drink and no US. Nicotine was administered every day of testing 30 min pri... [Read more]